Title:
新規プロモーター
Document Type and Number:
Japanese Patent JP3689103
Kind Code:
B2
Abstract:
Disclosing a promoter of the protease MDTS9, which is induced by TGF- beta , which is involved in the metabolism of extracellular matrix, and in which the expression of the gene thereof is elevated in renal failure model animals, which promoter is useful as a tool for screening an agent for treating and/or preventing chronic renal failure, as well as a method for screening an agent for treating and/or preventing chronic renal failure by selecting an inhibitor of the promoter.
Inventors:
Masataka Takeda
Kunitake Abe
Noboru Yamachi
Kunitake Abe
Noboru Yamachi
Application Number:
JP2004515521A
Publication Date:
August 31, 2005
Filing Date:
June 19, 2003
Export Citation:
Assignee:
Astellas Pharma Inc.
International Classes:
C12N15/09; A61K45/00; A61P13/12; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/64; C12Q1/02; C12Q1/68; A61K38/00; (IPC1-7): C12N15/09; A61K45/00; A61P13/12; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12Q1/02; C12Q1/68
Foreign References:
| WO2002031163A1 | ||||
| WO2001083782A1 |
Other References:
Database GenBank Accession No.AC010269, 23 Aug 2001
Attorney, Agent or Firm:
Morita Taku
Emiko Yano
Emiko Yano