Title:
新規蛋白質及びその製造方法
Document Type and Number:
Japanese Patent JP4878616
Kind Code:
B2
Abstract:
A novel protein which binds to Osteoclastogenesis Inhibitory Factor (OCIF-binding molecule; OBM), a process for preparing the same, DNA encoding said protein, a protein having an amino acid sequence encoded by this DNA, a method for producing said protein by genetic engineering technique, and a pharmaceutical composition containing said protein. Screening methods for a substance for controlling expression of said protein using said protein and the DNA, a substance which inhibits or modulates the biological activity of said protein, or a receptor which transmits the action of said protein through binding to said protein, the substance obtained by the screening methods, and a pharmaceutical composition which contains this substance. An antibody for said protein, a process for preparing the same, a measuring method of said protein using the antibody, and a medicine comprising this antibody.
Inventors:
Kyouji Yamaguchi
Naotaka Yasuda
Nobuaki Nakagawa
Nobuyuki Shima
Masahiko Kinosaki
Ei Tsuda
Masaaki Goto
Kazuki Yano
Tomoho Masataku
Fumie Kobayashi
Naohiro Washida
Ken Takahashi
Morinaga companion method
Koji Higashi
Naotaka Yasuda
Nobuaki Nakagawa
Nobuyuki Shima
Masahiko Kinosaki
Ei Tsuda
Masaaki Goto
Kazuki Yano
Tomoho Masataku
Fumie Kobayashi
Naohiro Washida
Ken Takahashi
Morinaga companion method
Koji Higashi
Application Number:
JP2008260450A
Publication Date:
February 15, 2012
Filing Date:
October 07, 2008
Export Citation:
Assignee:
Daiichi Sankyo Co., Ltd.
International Classes:
C07K14/715; C07K16/18; A61K38/00; A61K39/395; A61K45/00; A61P3/14; A61P19/00; A61P19/02; A61P19/08; A61P19/10; A61P29/00; A61P43/00; B01J20/281; C07K1/22; C07K14/47; C07K14/525; C07K14/705; C07K16/28; C12N5/10; C12N5/20; C12N15/02; C12N15/09; C12N15/12; C12P21/02; C12P21/08; G01N30/88; G01N33/15; G01N33/50; G01N33/53; G01N33/543; G01N33/566; G01N33/577; A61K; C07K; C12N; C12P; C12Q; G01N
Domestic Patent References:
| JP2001506991A | ||||
| JP2002509430A | ||||
| JP2001526532A |
Other References:
Nature, 1997.11.03, vol. 390, p. 175-179
Proc. Natl. Acad. Sci., 1998.03, vol. 95, p. 3597-3602
J. Biol. Chem., 1997.10.03, vol. 272, no. 40, p. 25190-25194
Biochem. Biophys. Res. Commun., 1997.05.08, vol. 234, p. 137-142
Proc. Natl. Acad. Sci., 1998.03, vol. 95, p. 3597-3602
J. Biol. Chem., 1997.10.03, vol. 272, no. 40, p. 25190-25194
Biochem. Biophys. Res. Commun., 1997.05.08, vol. 234, p. 137-142
Attorney, Agent or Firm:
Yoshio Ishii
Kyoko Yoshimi
Sanae Goto
Kiyoshi Fujino
Kyoko Yoshimi
Sanae Goto
Kiyoshi Fujino