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Title:
NEW SALICYLIC ACID DERIVATIVE, ITS USE IN COSMETIC AND/OR SKIN COMPOSITION
Document Type and Number:
Japanese Patent JP2983517
Kind Code:
B2
Abstract:

PROBLEM TO BE SOLVED: To obtain the subject new compound that can reduce irritation with acid and is useful in cosmetic and dermatologic fields, in addition useful for skin diseases in the fields of pharmacology and veterinary.
SOLUTION: This new compound is a salicylic acid derivative of the formula: AR-S2+AR- [S2+ is a divalent inorganic cation, preferably a cation in group IB, IIA, IIB, IIIB, IIIA and the like, for example, strontium, calcium, manganese; AR is a group of formula I (R5 is a 3-15C aliphatic chain)], typically 5-n- octanoylsalicylate salt. This compound is prepared by reaction of a salicylic acid derivative of formula II with a compound containing a divalent inorganic cation as bicarbonate salt, sulfate salt, glycerosulfate salt, borate salt or chloride salt in the presence of a solvent as a 1-12C alcohol, hydrocarbon, ketone, water, ether, amine, preferably isopropanol).


Inventors:
MISHERU FUIRITSUPU
KYASARIN KOOEN
Application Number:
JP11952998A
Publication Date:
November 29, 1999
Filing Date:
April 28, 1998
Export Citation:
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Assignee:
ROREARU
International Classes:
A61K8/00; A61K8/31; A61K8/33; A61K8/34; A61K8/30; A61K8/35; A61K8/37; A61K8/41; A61K31/00; A61K31/19; A61K31/60; A61P17/00; A61P17/10; A61Q19/00; C07C51/41; C07C65/05; C07C65/10; C07C65/32; C07C65/40; (IPC1-7): A61K7/48; A61K31/00; A61K31/60
Domestic Patent References:
JP6395977A
JP1025267A
Attorney, Agent or Firm:
Masatake Shiga (9 outside)