Title:
NEW SULFONAMIDE COMPOUNDS
Document Type and Number:
Japanese Patent JP2000319249
Kind Code:
A
Abstract:
To obtain a new compound useful as a medicine for treating or preventing virus infection, especially cytomegalovirus infection.
A compound of formula I [R1 is H, a (substituted) 6 to 10C aryl, (five to ten-membered aromatic heterogeneous ring) amino or the like; R2 is a 1 to 6C alkoxy, R1 or the like; R3 is H, a halogen, OH, a 1 to 6C acyl or the like; R4 and R5 are each a 1 to 3C alkyl, or R4 and R5 form a three to six-membered carbon ring together with the carbon atom bound to R4, R5; A is a (substituted) divalent 6 to 10C aryl, a (substituted) divalent five to ten- membered aromatic heterogeneous ring; D and E are each H, F, Cl, nitro, cyano or the like], for example, 5-({4-[(3-chloro-2,2-dimethylpropanoyl) amino]anilino}sulfonyl)-N-butyl-1-naphthalene acid amide. The compound of formula I can be produced, for example, by, if necessary, converting a compound of formula II into an acyl chloride or activating the compound of formula II, and then reacting the compound of formula II with a compound of formula III.
Inventors:
REEFSCHLAEGER JUERGEN
BENDER WOLFGANG
ECKENBERG PETER DR
GOLDMANN SIEGFRIED
HAERTER MICHAEL
HALLENBERGER SABINE
TRAPPE JOERG
WEBER OLAF
Application Number:
JP2000071933A
Publication Date:
November 21, 2000
Filing Date:
March 15, 2000
International Classes:
A61K31/18; A61K31/33; A61K31/341; A61K31/395; A61K31/40; A61K31/403; A61K31/404; A61K31/4045; A61K31/415; A61K31/426; A61K31/4375; A61K31/438; A61K31/44; A61K31/4402; A61K31/4418; A61K31/445; A61K31/4465; A61K31/4468; A61K31/45; A61K31/451; A61K31/472; A61K31/495; A61K31/496; A61K31/513; A61K31/535; A61K31/5375; A61K31/5377; A61K31/54; A61K31/551; A61P31/12; A61P31/22; C07C303/40; C07C311/21; C07D207/12; C07D207/20; C07D209/14; C07D209/16; C07D211/14; C07D211/22; C07D211/32; C07D211/46; C07D211/58; C07D211/62; C07D211/74; C07D213/40; C07D213/73; C07D213/74; C07D213/75; C07D213/77; C07D217/02; C07D217/22; C07D231/40; C07D239/46; C07D239/47; C07D243/08; C07D265/30; C07D273/00; C07D273/01; C07D277/04; C07D277/20; C07D277/46; C07D295/12; C07D295/16; C07D295/18; C07D295/192; C07D295/20; C07D295/205; C07D307/52; C07D471/04; C07D491/10; C07D491/113; (IPC1-7): C07C311/21; A61K31/18; A61K31/33; A61K31/341; A61K31/395; A61K31/40; A61K31/4045; A61K31/415; A61K31/426; A61K31/4375; A61K31/438; A61K31/44; A61K31/4402; A61K31/445; A61K31/45; A61K31/472; A61K31/495; A61K31/496; A61K31/513; A61K31/535; A61K31/5375; A61K31/5377; A61K31/54; A61K31/551; A61P31/22; C07C303/40; C07D207/12; C07D207/20; C07D209/16; C07D211/14; C07D211/22; C07D211/32; C07D211/46; C07D211/58; C07D211/62; C07D211/74; C07D213/40; C07D213/73; C07D213/74; C07D213/75; C07D213/77; C07D217/22; C07D231/40; C07D239/47; C07D243/08; C07D265/30; C07D273/01; C07D277/04; C07D277/46; C07D295/12; C07D295/16; C07D295/18; C07D295/20; C07D307/52; C07D471/04; C07D491/113
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)
