Title:
新規ウイルス複製阻害剤
Document Type and Number:
Japanese Patent JP2013501034
Kind Code:
A
Abstract:
The present invention relates to a series of novel compounds having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to methods for the preparation of such compounds, as well as to novel intermediates useful in one or more steps of such syntheses. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutical amount of such compounds, optionally combined with one or more other drugs having antiviral activity.
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Inventors:
Chartin, Patrick
Christo, Frauke
De Meyer, Marc
De Bezel, Zegel
Marchand, Arnault
Marchian, Damien
Smet, Wim
Foot, Arnault
Christo, Frauke
De Meyer, Marc
De Bezel, Zegel
Marchand, Arnault
Marchian, Damien
Smet, Wim
Foot, Arnault
Application Number:
JP2012523345A
Publication Date:
January 10, 2013
Filing Date:
August 05, 2010
Export Citation:
Assignee:
Catholic University Louvain
International Classes:
C07D239/26; A61K31/505; A61K31/506; A61K31/5377; A61K31/55; A61K31/551; A61K45/00; A61P31/12; A61P31/18; A61P43/00; C07D239/42; C07D401/04; C07D403/04; C07D405/04; C07D409/04; C07D413/14; C07D417/04; C07D491/06
Domestic Patent References:
| JPS6140272A | 1986-02-26 | |||
| JP2002535325A | 2002-10-22 | |||
| JP2005500294A | 2005-01-06 | |||
| JP2006524645A | 2006-11-02 | |||
| JP2003520272A | 2003-07-02 |
Foreign References:
| WO2008069609A1 | 2008-06-12 | |||
| WO2007062677A1 | 2007-06-07 | |||
| CS231636B1 | 1984-12-14 | |||
| WO2008016522A2 | 2008-02-07 | |||
| DE102007061766A1 | 2009-06-25 |
Other References:
CHEMICAL & PHARMACEUTICAL BULLETIN, vol. 36(5), JPN6014032301, 1988, pages 1664 - 8, ISSN: 0002866968
Attorney, Agent or Firm:
Shinjiro Ono
Yasushi Kobayashi
Hiroyuki Tomita
Osamu Hoshino
Mitsutoshi Nakamura
Yasushi Kobayashi
Hiroyuki Tomita
Osamu Hoshino
Mitsutoshi Nakamura