Title:
消炎、鎮痛および抗血栓活性を有するニトロ化合物およびそれらの組成物
Document Type and Number:
Japanese Patent JP4043046
Kind Code:
B2
Abstract:
PCT No. PCT/EP95/01233 Sec. 371 Date Mar. 6, 1997 Sec. 102(e) Date Mar. 6, 1997 PCT Filed Apr. 4, 1995 PCT Pub. No. WO95/30641 PCT Pub. Date Nov. 16, 1995New compounds and their compositions having anti-inflammatory, analgesic and anti-thrombotic activities, of the general formula: A-X1-NO2 or their salts, wherein: A is R(COXu)t, wherein t is zero or 1 and u is zero or 1; and X is O, NH or NR1C wherein R1C is C1-C10 alkyl; and R is(Ia) wherein R1 is acetoxoy, preferably n ortho-position with respect to -CO- and R2 is hydrogen; or derivatives of acetylsalylsalicyclic acid; and X1 is -YO- wherein Y is C1-C20 alkylene, C5-C7 cycloalkylene, oxy-alkyl derivatives and oxy-methyl benzyl derivatives.
Inventors:
Del Soldato, Clown
San Nicolo, Francisco
San Nicolo, Francisco
Application Number:
JP52861595A
Publication Date:
February 06, 2008
Filing Date:
April 04, 1995
Export Citation:
Assignee:
NICOX S.A.
International Classes:
C07C203/04; C07D333/22; A61K31/04; A61K31/21; A61K31/215; A61K31/24; A61K31/35; A61K31/38; A61K31/381; A61K31/40; A61K31/403; A61K31/4035; A61K31/405; A61K31/415; A61K31/42; A61K31/425; A61K31/44; A61K31/4433; A61K31/54; A61P7/02; A61P9/08; A61P9/10; A61P25/04; A61P29/00; A61P31/04; A61P43/00; C07C203/10; C07C205/41; C07C205/45; C07C211/54; C07C211/56; C07C225/22; C07C229/40; C07C233/16; C07C245/08; C07C323/62; C07D207/08; C07D209/28; C07D209/46; C07D213/74; C07D213/75; C07D213/76; C07D231/12; C07D261/08; C07D313/14; C07D333/24; C07D337/14; C07D409/06; C07D417/12; C07D487/04; C07D491/052; C07D513/04
Domestic Patent References:
| JP3775796B2 | ||||
| JP3231043B2 | ||||
| JP5508841A | ||||
| JP8504191A |
Foreign References:
| WO1994004484A1 |
Attorney, Agent or Firm:
Shintaro Nogawa