Title:
カルボン酸基を含む窒素含有ベンゾ複素環化合物、その調製方法及び使用
Document Type and Number:
Japanese Patent JP7263659
Kind Code:
B2
Abstract:
Related is a nitrogen-containing benzoheterocycle compound containing a carboxylic acid group as shown in general formula (I), or a stereoisomer or pharmaceutically acceptable salt thereof. The compound has excellent pharmacokinetic properties and extremely remarkable liver targeting properties, and a pharmaceutical composition comprising the same may be used as a CCR antagonist, in particular a CCR2 and/or CCR5 antagonist and can be used in mediated disease, including, but not limited to, nonalcoholic fatty liver disease (NAFLD) or the like.
More Like This:
Inventors:
Song, Shuai
Tian, Chan
Woo, Young Young
Xiao, Mingliang
Wang, Chao Lay
Kai, Jiaqiang
One, Lichun
Wan, Jin Yi
Tian, Chan
Woo, Young Young
Xiao, Mingliang
Wang, Chao Lay
Kai, Jiaqiang
One, Lichun
Wan, Jin Yi
Application Number:
JP2020536998A
Publication Date:
April 25, 2023
Filing Date:
January 18, 2019
Export Citation:
Assignee:
Situan Cologne-Biotech Bioffer Matthewical Company Limited
International Classes:
C07D403/12; A61K31/55; A61P1/16; A61P3/06; A61P35/00; A61P43/00
Domestic Patent References:
| JP2004123694A | ||||
| JP2003335776A | ||||
| JP2017509704A |
Foreign References:
| WO2016187393A1 | ||||
| WO2016105527A1 |
Attorney, Agent or Firm:
Ikeda Adult
Junichiro Sakamaki
Masakazu Noda
Junichiro Sakamaki
Masakazu Noda
Previous Patent: Method for protecting human skin from damage upon exposure to blue light
Next Patent: MOS CONTROL TYPE THYRISTOR
Next Patent: MOS CONTROL TYPE THYRISTOR