Title:
含窒素複素環化合物またはその塩
Document Type and Number:
Japanese Patent JP5736507
Kind Code:
B2
Abstract:
The object is to provide an Fms-like tyrosine kinase 3 (FLT3) inhibitor useful as a therapeutic agent for acute myeloid leukemia (AML). A novel nitrogen-containing heterocyclic compound represented by the general formula [1] or a salt thereof is provided. The compound or a salt thereof of the present invention can be used as an active ingredient of a pharmaceutical composition for a treatment of a disease or condition relating to FLT3, such as acute myeloid leukemia (AML) and acute promyelocytic leukemia (APL).
Inventors:
Takasaki Yu
Toshiaki Tsujino
Shintaro Tanabe
Megumi Okubo
Kimihiko Sato
Atsushi Hirai
Daisuke Terada
Shinsuke Inuki
Mizumoto Shinsuke
Toshiaki Tsujino
Shintaro Tanabe
Megumi Okubo
Kimihiko Sato
Atsushi Hirai
Daisuke Terada
Shinsuke Inuki
Mizumoto Shinsuke
Application Number:
JP2014511220A
Publication Date:
June 17, 2015
Filing Date:
April 16, 2013
Export Citation:
Assignee:
FUJIFILM Corporation
International Classes:
C07D213/74; A61K31/44; A61K31/505; A61K31/506; A61K31/5377; A61K31/55; A61K31/551; A61P35/02; A61P43/00; C07D213/75; C07D239/47; C07D239/48; C07D401/06; C07D401/12; C07D401/14; C07D403/12; C07D405/04; C07D405/06; C07D405/12; C07D405/14; C07D409/12; C07D413/04; C07D413/12; C07D417/12; C07D471/04
Foreign References:
| WO2011034907A2 | 2011-03-24 | |||
| WO2009158571A1 | 2009-12-30 | |||
| WO2009145856A1 | 2009-12-03 | |||
| WO2008155140A1 | 2008-12-24 | |||
| WO2011034907A2 | 2011-03-24 | |||
| WO2009158571A1 | 2009-12-30 | |||
| WO2009145856A1 | 2009-12-03 | |||
| WO2008155140A1 | 2008-12-24 |
Other References:
JPN6015001184; ＩＳＨＩＤＡ Ｈ． ｅｔ ａｌ．: Ｂｉｏｏｒｇ． Ｍｅｄ． Ｃｈｅｍ． Ｌｅｔｔ． Ｖｏｌ．１８, 2008, ｐ．５４７２-７
JPN6015001184; ＩＳＨＩＤＡ Ｈ． ｅｔ ａｌ．: Ｂｉｏｏｒｇ． Ｍｅｄ． Ｃｈｅｍ． Ｌｅｔｔ． Ｖｏｌ．１８, 2008, ｐ．５４７２-７
JPN6015001184; ＩＳＨＩＤＡ Ｈ． ｅｔ ａｌ．: Ｂｉｏｏｒｇ． Ｍｅｄ． Ｃｈｅｍ． Ｌｅｔｔ． Ｖｏｌ．１８, 2008, ｐ．５４７２-７
Attorney, Agent or Firm:
Patent Service Corporation Patent Office Sykes