Title:
NITROSATED NONSTEROIDAL ANTIINFLAMMATORY COMPOUND, COMPOSITION AND METHOD OF USE
Document Type and Number:
Japanese Patent JP2010280665
Kind Code:
A
Abstract:
To provide a new NSAID (nitrosated nonsteroidal antiinflammatory drug), a composition and a method for using the same.
There are provided an NSAID of the formula, its pharmaceutically acceptable salt, and a new composition containing at least one nitrosated NSAID and optionally at least one compound that donates, transfers or releases nitric oxide, stimulates endogenous synthesis of nitric oxide, elevates endogenous levels of endothelium-derived blood vessel relaxing factor or is a substrate for a nitric oxide synthase, and/or at least one therapeutic agent. There are further provided a new kit containing the therapeutic agent and a method for treatment and/or prevention.
Inventors:
EARL RICHARD A
EZAWA MAIKO
FANG XINQIN
GARVEY DAVID S
GASTON RICKY D
KHANAPURE SUBHASH P
LETTS GORDON L
LIN CHIA-EN
RANATUNGE RAMANI R
RICHARDSON STEWART K
SCHROEDER JOSEPH D
STEVENSON CHERI A
WEY SHIOW-JYI
EZAWA MAIKO
FANG XINQIN
GARVEY DAVID S
GASTON RICKY D
KHANAPURE SUBHASH P
LETTS GORDON L
LIN CHIA-EN
RANATUNGE RAMANI R
RICHARDSON STEWART K
SCHROEDER JOSEPH D
STEVENSON CHERI A
WEY SHIOW-JYI
Application Number:
JP2010155441A
Publication Date:
December 16, 2010
Filing Date:
July 08, 2010
Export Citation:
Assignee:
NICOX SA
International Classes:
C07C203/04; A61K31/21; C07D295/08; A61K31/34; A61K31/357; A61K31/405; A61K31/445; A61K31/495; A61K45/00; A61P1/00; A61P1/04; A61P1/10; A61P1/14; A61P3/04; A61P9/00; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P13/00; A61P13/02; A61P13/12; A61P15/00; A61P15/10; A61P17/00; A61P17/02; A61P19/02; A61P21/00; A61P25/00; A61P25/04; A61P25/28; A61P27/02; A61P29/00; A61P31/04; A61P35/00; A61P35/02; A61P37/06; A61P43/00; C07C205/40; C07C205/56; C07C219/10; C07C229/42; C07C235/08; C07C235/12; C07C235/34; C07C235/42; C07C237/08; C07C243/28; C07C271/16; C07C271/64; C07C291/02; C07C311/17; C07C317/18; C07C317/32; C07C317/46; C07C323/12; C07C327/28; C07D209/18; C07D209/28; C07D211/22; C07D211/40; C07D211/56; C07D295/00; C07D319/06; C07D493/04; C07F9/40
Domestic Patent References:
| JPH09512798A | 1997-12-22 | |||
| JP2004512303A | 2004-04-22 | |||
| JPH09503214A | 1997-03-31 | |||
| JPH07500355A | 1995-01-12 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Kazuya Kawamoto
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