NKT CELL-LACKING ANIMAL AND NKT CELL-POSSESSING ANIMAL

Title:

NKT CELL-LACKING ANIMAL AND NKT CELL-POSSESSING ANIMAL

Document Type and Number:

Japanese Patent JPH10271933

Kind Code:

A

Abstract:

To obtain NKT cell-lacking non-human animal useful for elucidation of mechanism of the function and differentiation of NKT cell, elucidation of diseases possibly involved in the action of NKT cell, and research for treatment of the diseases and so on.

This animal has NKT cell in which uniform Vα14 and/or Jα281α chain or Jα281 gene is deleted. This non-human animal such as mouse has preferably only Vα14-positive NKT cell as mature lymphocyte, and is a transgenic animal expressing Vα14 and Vβ8.2.

Inventors:

TANIGUCHI KATSU
SAI SHIYUNSEI
KOSEKI AKIHIKO

Application Number:

JP8095097A

Publication Date:

October 13, 1998

Filing Date:

March 31, 1997

Export Citation:

Click for automatic bibliography generation Help

Assignee:

TANIGUCHI KATSU

International Classes:

C12N15/09; A01K67/027; (IPC1-7): A01K67/027; C12N15/09

Attorney, Agent or Firm:

Akira Asamura (3 outside)

Previous Patent: SINK-AND-FLOAT TYPE WIRE NET CAGE FOR FISH-AND-SHELLFISH CULTURE AND CULTURE OF FISH-AND-SHELLFISH

Next Patent: ROD FOR FISHING ROD USE