Title:
置換エナミノン類、それらの誘導体およびそれらの使用
Document Type and Number:
Japanese Patent JP5002452
Kind Code:
B2
Abstract:
The invention relates to substituted enaminones of Formula I and their derivatives and the discovery that these compounds modulate the effect of γ-aminobutyric acid (GABA) on the GABAA receptor complex in a therapeutically relevant fashion and may be used to ameliorate CNS disorders amenable to modulation of the GABAA receptor complex.
Inventors:
Hogenkamp, Delk Jay.
Johnston, Timothy B. C.
Gee, Kelvin W.
Johnston, Timothy B. C.
Gee, Kelvin W.
Application Number:
JP2007511639A
Publication Date:
August 15, 2012
Filing Date:
May 05, 2005
Export Citation:
Assignee:
The Regents of The University of California
International Classes:
C07C237/20; A61K31/137; A61K31/165; A61K31/275; A61K31/42; A61K31/439; A61K31/4965; A61P25/00; A61P25/04; A61P25/06; A61P25/08; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P25/36; A61P43/00; C07C211/00; C07C225/16; C07C229/34; C07C243/22; C07C255/58; C07D241/20; C07D249/08; C07D261/14; C07D317/66; C07D487/08
Domestic Patent References:
| JP7500611A |
Foreign References:
| WO2003097564A1 | ||||
| US5622967 | ||||
| WO1994027993A1 | ||||
| WO1993013091A1 | ||||
| ES2049640A1 |
Other References:
Synthetic Communications ,2000年,Vol.30, No.14,P.2533-2540
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita