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Title:
アレルギーの予防及び治療のためのプロバイオティクスから得られる非生存型物質
Document Type and Number:
Japanese Patent JP2013504321
Kind Code:
A
Abstract:
Disclosed is a process for the preparation of a non-viable probiotic composition having anti-allergic (i.e. allergy preventive and/or anti-allergic in a therapeutic sense, and/or anti-inflammatory properties, the process comprising the steps of (a) subjecting LGG to cultivation in a suitable culture medium using a batch process; (b) harvesting the culture supernatant at a late exponential phase of the cultivation step; (c) removing liquid contents from the culture supernatant so as to obtain the composition. Also disclosed is a composition comprising a proteinaceous mixture obtainable by the above process, and the use thereof in a dietetic product preferably for targeting expecting mother's, infants, or children as well as application in food for specific medical purposes.

Inventors:
Fantle, Eric, A.F.
Russell, William, Michael
Hertz, Udo
Lenz, Harald
Garn, Holger
Black bear, macert
Van der Werff, Maria, Johanna
Auferkamp, Karin, Em
Application Number:
JP2012528768A
Publication Date:
February 07, 2013
Filing Date:
September 10, 2010
Export Citation:
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Assignee:
MEAD JOHNSON NUTRITION COMPANY
International Classes:
C12N1/20; A23L1/30; A23L29/00; A61K31/202; A61K31/70; A61K31/715; A61K33/00; A61K35/74; A61K38/00; A61P37/00
Domestic Patent References:
JP2006519014A2006-08-24
Foreign References:
WO2006113035A12006-10-26
Other References:
JPN6014051195; 原田岳ら: アレルギーの臨床 Vol.28, No.13, 2008, pp.1159-1162
JPN5012017703; POHJAVUORI, E., et al.: 'LACTOBACILLUS GG EFFECT IN INCREASING IFN-GAMMA PRODUCTION IN INFANTS WITH COW'S MILK ALLERGY' JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY Vol.114, No.1, 200407, pp.131-136
JPN5012017698; PENA, J.A., et al: 'LACTOBACILLUS RHAMNOSUS GG DECREASES TNF-ALPHA PRODUCTION 以下備考' CELLULAR MICROBIOLOGY Vol.5, No.4, 2003, pp.277-285, BLACKWELL SCIENCE
JPN5012017701; CHOI, C.H., et al.: 'EFFECT OF LACTOBACILLUS GG AND CONDITIONED MEDIA ON IL-1 BETA-INDUCED 以下備考' SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY Vol.43, No.8, 2008, pp.938-947
Attorney, Agent or Firm:
Hideo Takino
Takao Kawasaki
Fumio Takino
Toshiaki Tsuda
Masashi Torino
Park Ji-un