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Title:
NOVEL 1,5-BENZOTHIAZEPINES, MANUFACTURE AND PHARMACEUTICAL COMPOSITION
Document Type and Number:
Japanese Patent JPS6042374
Kind Code:
A
Abstract:
New 1,5-benzothiazepines of the following general formula I wherein: R1 represents (C1-4)alkyl, (C1-4)alkoxy or a halogen atom; R2 is selected from: benzoyl independently substituted with 1 to 3 (C1-4)alkyl or (C1-4)alkoxy groups, or with halogen atoms; phenylcarbamoyl; phenylcarbamoyl independently substituted with 1 to 3 (C1-4) alkyl or (C1-4) alkoxy groups or with halogen atoms; the groups R5-CO, in which R5 is the radical deriving from a heterocyclic ring optionally substituted by a (C1-4)alkyl or a (C1-4)alkoxy radical, or by a halogen atom; R3 and R4 independently represent (C1-4)alkyl groups; and salts therewith of pharmaceutically acceptable acids. The compounds of the invention possess cardiovascular utility.

Inventors:
SUTEFUANO MAIORAANA
DEIEGO BUROKETSUTEI
JIYUZETSUPE PIACHIENZA
AMEDEA MANFUREDEI
Application Number:
JP14976684A
Publication Date:
March 06, 1985
Filing Date:
July 20, 1984
Export Citation:
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Assignee:
SHIYATSUPARERI PHARM SPA
International Classes:
A61K31/55; A61K31/554; A61P9/08; A61P9/10; C07D281/10; C07D417/12; (IPC1-7): A61K31/55; C07D213/00; C07D281/00; C07D281/10; C07D417/12
Domestic Patent References:
JP46043784A
Attorney, Agent or Firm:
Heikichi Odashima