Title:
肝臓の画像化用配位子としての新規なＤＡＺＡキレート剤
Document Type and Number:
Japanese Patent JP7299911
Kind Code:
B2
Abstract:
The invention relates to compounds according to the general formula (I) or a pharmaceutically acceptable salt of an inorganic or organic acid, a hydrate, a stereoisomer or a solvate thereof, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 being selected independently of one another from hydrogen and alkoxy. The compounds of formula (I) as ligands are suitable for the production of radioactively labelled 68Ga, 64Cu, 67Ga, 111In or 99mTc complexes. The invention further relates to a method for producing the compounds of formula (I) and the radioactively labelled complexes and to the use of the radioactively labelled complexes in imaging methods, such as PET/CT, in particular of the liver.
Inventors:
Martin Friesmayer
Julia Gracel
Julia Gracel
Application Number:
JP2020550907A
Publication Date:
June 28, 2023
Filing Date:
December 10, 2018
Export Citation:
Assignee:
X-Nuclear Diagnostics GmbH
International Classes:
C07D243/08; A61K51/04; A61P1/16; C07B59/00; C07F1/08; C07F5/00; C07F13/00
Foreign References:
| WO2014198478A1 | ||||
| US20170327520 | ||||
| WO2012095347A1 | ||||
| KR1020170089245A | ||||
| US20170121368 |
Other References:
Nuclear Medicine and Biology,1995年,22(7),859-868
Nuclear Medicine and Biology,1996年,23(5),645-652
ARKIVOC,2006年,(4),212-233
Dalton Transactions,2018年,47(27),9000-9007
Nuclear Medicine and Biology,1996年,23(5),645-652
ARKIVOC,2006年,(4),212-233
Dalton Transactions,2018年,47(27),9000-9007
Attorney, Agent or Firm:
Toru Ishikawa
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