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Title:
NOVEL AMINOSULFONYLBENZOIC ACID ESTER DERIVATIVE
Document Type and Number:
Japanese Patent JPS58192863
Kind Code:
A
Abstract:

NEW MATERIAL:The compound of formula (X and Y are F, Cl, Br or H; R is alkyl, alkenyl, cycloalkyl or benzyl).

EXAMPLE: 5-Aminosulfonyl-2,4-dichlorobenzoic acid benzyl ester.

USE: Antiviral agent.

PROCESS: The aminosufonylbenzoic acid ester of formula can be prepared by (1) heating a halogenoaminosulfonylbenzoic acid in thionyl chloride, and (2) reacting the resultant halogenoaminosulfonylbenzoyl chloride with an alcohol of formula ROH at room temperature or if necessary under heating in a solvent such as dioxane, THF, benzene, etc. or using the alcohol of formula ROH as the solvent.


Inventors:
Maeda, Hideo
Kono, Shoichi
Onishi, Haruo
Application Number:
JP1982000075781
Publication Date:
November 10, 1983
Filing Date:
May 06, 1982
Export Citation:
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Assignee:
HODOGAYA CHEM CO LTD
MOCHIDA PHARMACEUT CO LTD
International Classes:
A61K31/18; A61P31/12; C07C67/00; C07C301/00; C07C311/21; C07C311/49; C07C311/64; C07D237/20; C07D295/26; (IPC1-7): A61K31/18; C07C143/78



 
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