新規駆虫薬化合物

Japanese Patent JP7459082

B2

The present invention relates to novel compounds of general formula (I):withAbeing A1 or A²:andin which T, X, Y, Ro, R¹, R¹⁰and R¹¹are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the said compounds for use in the treatment, control and/or prevention of diseases, in particular of helminth infections, as a sole agent or in combination with other active ingredients.

Niles, Gleebenau
Hypsch, Walter
Schwarz, Hans-Georg
Chuwan, Way
Arrig, Bernd
Ahrine, Koehler
Kurke, Daniel
Heissler, Ealing
Irg, Thomas

JP2021521984A

April 01, 2024

October 23, 2019

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Elanco Animal Health GmbH

C07D241/42; A61K31/353; A61K31/37; A61K31/381; A61K31/404; A61K31/4192; A61K31/4365; A61K31/437; A61K31/4375; A61K31/4439; A61K31/4725; A61K31/498; A61K31/5377; A61P33/10; C07D249/20; C07D311/58; C07D311/68; C07D405/12; C07D405/14; C07D409/12; C07D471/04; C07D495/04

WO2018087036A1
WO2017178416A1
WO2017143041A1
WO2020014068A1

Journal of Chromatography A ,1994年,666(1-2),41-53
European Journal of Organic Chemistry ,2016年,196-209
Tetrahedron: Asymmetry ,2016年,27,614-622
Journal of Medicinal Chemistry ,1990年,33(9),2667-72
Heterocyclic Letters,2012年,2(3),253-261

Makoto Ono
Kennori Kanayama
Yoshiyuki Tsubokura
Kazuki Shigemori
Kenji Ando
Hidehiko Ichikawa
Yoshie Sakurada
Yosuke Kawasaki
Takuya Gomibuchi
Youichi Iino
Yusuke Ichikawa
Masahiro Moriyama
Takashi Kawano
Yoshikazu Iwase
Yasufumi Shiroyama

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