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Title:
NOVEL ANTIBIOTIC PIPERAZINOMYCIN AND ITS PREPARATION
Document Type and Number:
Japanese Patent JPS58170785
Kind Code:
A
Abstract:

NEW MATERIAL:An antibiotic having the following properties. Appearance: colorless amorphous powder, specific rotatory power: [α]20D+31.1° (c=0.74, methanol), Rf value of thin layer chromatography of silica gel 60F254:0.67 [developing solvent chloroform-methanol- 14% ammonia water (7:3:2) bottom layer], solubility: easily soluble in methanol, soluble in pyridine, slightly soluble in ethyl acetate, chloroform or acetone, and insoluble in n-hexane, benzene, or water, positive in ninhydrin reaction, positive in red prussiate-ferric chloride reaction.

USE: An antibacterial agent.

PROCESS: A bacterium (FERM-P 4376) belonging to the genus Streptoverticillium, capable of producing piperazinomycin, is cultivated in a nutritive medium, and piperazinomycin is produced, accumulated, and collected.


Inventors:
NAKAMURA AKISHIROU
KANEDA MIYUKI
UMEZAWA HAMAO
Application Number:
JP5231482A
Publication Date:
October 07, 1983
Filing Date:
April 01, 1982
Export Citation:
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Assignee:
MICROBIAL CHEM RES FOUND
International Classes:
A61K31/495; A61P31/04; C07D498/08; C12P7/18; C12P17/18; C12R1/01; (IPC1-7): A61K31/495; C07D498/08; C12P17/18
Domestic Patent References:
JPS5097208U1975-08-13
JPS5220884Y21977-05-13
JPS5220885Y21977-05-13
Attorney, Agent or Firm:
Shigeru Yagita