Title:
NOVEL BETA-LACTAM DERIVATIVE
Document Type and Number:
Japanese Patent JPS58208292
Kind Code:
A
Abstract:
3-Heterocyclylamino-ethylthio- 6-substd.-7-oxo carbapen-2-em-2-carboxylic acids and their S-oxides of formula (I) and their salts and esters are new. (R is 1-6C alkyl or 3-6C alkenyl; n is 0 or 1; and ring X is a mono- or poly-cyclic N-contg. heterocyclic gp.) (I) in which R is Et and the H atoms at C5 and C6 are trans are pref. (I) are broad-spectrum antibacterials useful as therapeutic agents in man and animals and as industrial bactericides e.g. food preservatives, disinfectants, etc. Dose is 5-500 mg/kg daily.
Inventors:
AMEDEO OMODEIISARE
DOUSHIO FUABARA
PIETORO KONSONI
ROBERUTO SETSUKI
DOUSHIO FUABARA
PIETORO KONSONI
ROBERUTO SETSUKI
Application Number:
JP8161883A
Publication Date:
December 03, 1983
Filing Date:
May 10, 1983
Export Citation:
Assignee:
LEPETIT SPA
International Classes:
A61K31/397; A61K31/40; A61P31/04; C07C205/42; C07D205/08; C07D213/74; C07D213/75; C07D233/88; C07D261/14; C07D277/42; C07D277/46; C07D477/00; C07D477/20; C07D519/00; (IPC1-7): A61K31/40; A61K31/41; A61K31/415; A61K31/42; A61K31/425; A61K31/435; A61K31/44; A61K31/445; A61K31/495; A61K31/50; A61K31/505; A61K31/53; A61K31/535; C07D205/08; C07D487/04; C07D519/00
Attorney, Agent or Firm:
Asamura Akira
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