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Patent Searching and Data


Title:
NOVEL CATIONIC POLYPHOSPHAZENE COMPOUNDS, POLYPHOSPHAZENE-DRUG CONJUGATE COMPOUNDS AND METHODS FOR PREPARING THE SAME
Document Type and Number:
Japanese Patent JP2019123878
Kind Code:
A
Abstract:
To provide new substances which have excellent cancer tissue selectivity and very low toxicity and are likely to be implemented as anticancer drugs.SOLUTION: The present invention can apply: cationic linear polyphosphazene compounds into which a hydrophilic poly(ethylene glycol) and a spacer group selected from the group consisting of lysine, oligopeptides containing lysine, amino-ethanol, amino-propanol, amino-butanol, amino-pentanol and amino-hexanol are introduced; polyphosphazene-drug conjugate compounds obtained by chemically bonding hydrophobic drugs to the compounds; and preparation methods thereof.SELECTED DRAWING: Figure 12

Inventors:
ソン, ヨン ソ
ジュン, ヨン ジョ
アヴァジ, プラカシュ ゴーダ
Application Number:
JP2019045513A
Publication Date:
July 25, 2019
Filing Date:
March 13, 2019
Export Citation:
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Assignee:
シーエヌファーム・カンパニー・リミテッド
CNPHARM CO., LTD.
ソン, ヨン ソ
SOHN, Youn Soo
International Classes:
C08G79/025; A61K31/282; A61K31/337; A61K31/4745; A61K47/59; A61K47/65; A61P35/00; C08G81/00
Attorney, Agent or Firm:
前田・鈴木国際特許業務法人