Title:
NOVEL CELL-PENETRATING COMPOSITIONS AND METHODS USING THE SAME
Document Type and Number:
Japanese Patent JP2020072716
Kind Code:
A
Abstract:
To provide novel molecules useful in promoting the delivery of cargo molecules across cell membranes, such as therapeutic agents, nucleic acids, peptides, saccharides, lipids, and liposomes.SOLUTION: The present invention includes an isolated transport peptide, which crosses the cell membrane of a cell and/or binds to a target cell. The present invention also includes a transport construct in which a transport peptide is linked to a cargo moiety to be delivered into a cell. The present invention further includes a method of delivering a transport construct into and/or to a cell.SELECTED DRAWING: Figure 1
Inventors:
WILLIAM C SESSA
FRANK J GIORDANO
FRANK J GIORDANO
Application Number:
JP2020001263A
Publication Date:
May 14, 2020
Filing Date:
January 08, 2020
Export Citation:
Assignee:
UNIV YALE
International Classes:
A61K45/00; A61K47/42; A61K47/64; C07K7/06; C07K14/47; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/071; C12N5/077; C12N5/078; C12N5/079; C12N5/10; C12N7/00; C12N15/11; C12N15/12; C12N15/62; C12N15/63
Domestic Patent References:
| JP2011514160A | 2011-05-06 | |||
| JP2005503321A | 2005-02-03 | |||
| JP2016539188A | 2016-12-15 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto