Title:
NOVEL COMPOUND LENTZTREHALOSE, METHOD OF PRODUCING THE SAME AND USE THEREOF, AND NOVEL MICROORGANISMS
Document Type and Number:
Japanese Patent JP2014227404
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a novel compound that has excellent antitumor action, excellent bone strengthening action or excellent weight gain inhibitory action, and is available also as a sweetener, and a method of producing the novel compound.SOLUTION: From a culture of microorganisms belonging to the genus Lentzea such as Lentzea sp. ML457-mF8 strain (NITEP-01586), a trehalose derivative of a novel structural formula is separated. It is also possible for the production of the compound by a genetic engineering method.
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Inventors:
WADA SHUNICHI
OBA SHUNICHI
SOMENO TETSUYA
HATANO KAZUKI
OBA SHUNICHI
SOMENO TETSUYA
HATANO KAZUKI
Application Number:
JP2013110521A
Publication Date:
December 08, 2014
Filing Date:
May 27, 2013
Export Citation:
Assignee:
INST OF MICROBIAL CHEMISTRY
International Classes:
C07H15/04; A23L1/30; A23L27/00; A23L27/30; A23L33/20; A61K31/7016; A61P3/04; A61P19/08; A61P35/00; C12N1/20; C12P19/12
Domestic Patent References:
| JP2002518045A | 2002-06-25 | |||
| JP2008520543A | 2008-06-19 |
Foreign References:
| WO2010050178A1 | 2010-05-06 |
Other References:
UKAWA, Y. ET AL.: "Antitumor Effect of Trehalose on Sarcoma 180 in ICR Mice", JOURNAL OF APPLIED GLYCOSCIENCE, vol. 52, JPN6017002013, 2005, pages 367 - 368, ISSN: 0003532238
VILLANDIER, N. ET AL.: "Selective synthesis of amphiphilic hydroxyalkylethers of disaccharides over solid basic catalysts In", JOURNAL OF MOLECULAR CATALYSIS A: CHEMICAL, vol. 259, JPN6017002015, 2006, pages 67 - 77, XP028015191, ISSN: 0003532239, DOI: 10.1016/j.molcata.2006.06.008
VILLANDIER, N. ET AL.: "Selective synthesis of amphiphilic hydroxyalkylethers of disaccharides over solid basic catalysts In", JOURNAL OF MOLECULAR CATALYSIS A: CHEMICAL, vol. 259, JPN6017002015, 2006, pages 67 - 77, XP028015191, ISSN: 0003532239, DOI: 10.1016/j.molcata.2006.06.008
Attorney, Agent or Firm:
Koichi Hirota
流 Yoshihiro
Naoko Matsuda
流 Yoshihiro
Naoko Matsuda
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