Title:
NOVEL COMPOUNDS AND COMPOSITIONS FOR INHIBITION OF NAMPT
Document Type and Number:
Japanese Patent JP2016199556
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide compounds and compositions for inhibition of nicotinamide phosphoribosyl transferase (NAMPT), their synthesis, applications and antidotes.SOLUTION: The present invention provides a compound represented by formula IC, or pharmaceutically acceptable salt thereof [R1 is NRH, or substituted/unsubstituted cycloalkyl, aryl, heterocycloalkyl or heteroaryl].SELECTED DRAWING: None
Inventors:
KENNETH W BAIR
TIMM BAUMEISTER
ALEXANDRE J BUCKMELTER
KARL H CLODFELTER
HAN BINGSONG
LIN JIAN
DOMINIC J REYNOLDS
CHASE C SMITH
WANG ZHONGGUO
ZHENG XIAOZHANG
TIMM BAUMEISTER
ALEXANDRE J BUCKMELTER
KARL H CLODFELTER
HAN BINGSONG
LIN JIAN
DOMINIC J REYNOLDS
CHASE C SMITH
WANG ZHONGGUO
ZHENG XIAOZHANG
Application Number:
JP2016112149A
Publication Date:
December 01, 2016
Filing Date:
June 03, 2016
Export Citation:
Assignee:
FORMA TM LLC
International Classes:
C07D213/56; A61K31/4406; A61K31/455; A61K31/5383; A61K31/706; A61K45/00; A61P1/04; A61P3/00; A61P3/10; A61P9/10; A61P11/06; A61P11/08; A61P13/12; A61P17/00; A61P17/04; A61P17/06; A61P19/02; A61P19/10; A61P25/28; A61P29/00; A61P31/12; A61P31/18; A61P31/22; A61P35/00; A61P35/02; A61P37/06; A61P43/00; C07D498/08
Domestic Patent References:
| JP5978293B2 | 2016-08-24 |
Attorney, Agent or Firm:
Sonoda/Kobayashi Patent Business Corporation
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