Title:
NOVEL CONDENSED PYRIMIDINE DERIVATIVE
Document Type and Number:
Japanese Patent JP2010037268
Kind Code:
A
Abstract:
To provide a compound or its pharmaceutically acceptable salt useful as a therapeutic and/or preventive agent for diseases related to CaMKII such as autoimmune diseases.
The compound is a condensed pyrimidine compound represented by formula (1) [wherein R1 is hydrogen, an alkyl group or the like; R2 is a substituted or nonsubstituted aryl group or the like, X is represented by formula (2) (wherein m is an integer of 0-5, Cy is a substituted or nonsubstituted phenyl or the like; and R4 and R5 are each hydrogen or the like), Y is NH, oxygen or the like and the ring A is a carbon ring, an N-containing heterocycle or the like] and includes its pharmacologically acceptable salt.
Inventors:
NAKATANI SHOGO
HASHIZUKA TAKAHIKO
ASANO NARUHIRO
HASHIZUKA TAKAHIKO
ASANO NARUHIRO
Application Number:
JP2008201878A
Publication Date:
February 18, 2010
Filing Date:
August 05, 2008
Export Citation:
Assignee:
DAINIPPON SUMITOMO PHARMA CO
International Classes:
C07D239/95; A61K31/517; A61K31/519; A61K31/55; A61P29/00; A61P35/00; A61P37/06; C07D471/04; C07D487/04
Attorney, Agent or Firm:
Yuki Ito
Yobe
Mayumi Matsuo
Horikawa Tamaki
Yobe
Mayumi Matsuo
Horikawa Tamaki
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