Title:
NOVEL HETEROCYCLIC ACETIC ACID DERIVATIVE AND MANUFACTURE
Document Type and Number:
Japanese Patent JPS58118566
Kind Code:
A
Abstract:
New heterocyclic acetic acid compounds of the general formula (I), wherein Y<1> and Y<2> form together a removable carbonyl protecting group, and R is a removable amido protecting group, are prepared in the way that a compound of the general formula (II), wherein R, Y<1> and Y<2> are as defined above, is activated on the carboxy group and then reacted with diazomethane, and the resulting new compound of the general formula (II), wherein R, Y<1> and Y<2> are as defined above, is subjected to diazoketone rearrangement in the presence of water. The new compounds according to the invention can be incorporated into pharmaceutical preparations and are valuable intermediates in the synthesis of thienamycin and thienamycin analogues.
Inventors:
KARORII REMUPERUTO
GABOORU DORESUSHIYAARU
YOZUSEFU FUETSUTAA
GIYURA HORUNYATSUKU
PEETAA FUSUZUSHII
YOZUSEFU NIITORAI
GIYURA SHIMIGU
KARORII ZAUERU
CHIBOORU GIZURU
KARUMAN HARUSANII
GIYORUGII FUEKETE
RASUZURO SUZUPORUNII
GIYORUGII HAYOSU
GABOORU DORESUSHIYAARU
YOZUSEFU FUETSUTAA
GIYURA HORUNYATSUKU
PEETAA FUSUZUSHII
YOZUSEFU NIITORAI
GIYURA SHIMIGU
KARORII ZAUERU
CHIBOORU GIZURU
KARUMAN HARUSANII
GIYORUGII FUEKETE
RASUZURO SUZUPORUNII
GIYORUGII HAYOSU
Application Number:
JP23500682A
Publication Date:
July 14, 1983
Filing Date:
December 24, 1982
Export Citation:
Assignee:
RICHTER GEDEON VEGYESZET
International Classes:
C07D205/08; C07D207/28; C07D405/04; C07D411/04; (IPC1-7): C07D205/08; C07D405/04
Domestic Patent References:
| JPS57167964A | 1982-10-16 |
Attorney, Agent or Firm:
Asamura Akira
Previous Patent: JPS58118565
Next Patent: SULFAMOYLBEZOIC ACID DERIVATIVE AND REMEDY COMPOSITION CONTAINING IT AS ACTIVE INGREDIENT
Next Patent: SULFAMOYLBEZOIC ACID DERIVATIVE AND REMEDY COMPOSITION CONTAINING IT AS ACTIVE INGREDIENT