Title:
NOVEL IMMUNOTHERAPY FOR SEVERAL TUMORS OF BLOOD, IN PARTICULAR CHRONIC LYMPHATIC LEUKEMIA (CLL)
Document Type and Number:
Japanese Patent JP2020014460
Kind Code:
A
Abstract:
To provide peptides for use in immunotherapy.SOLUTION: The invention relates to peptides, nucleic acids and cells. In particular, the invention relates to cancer immunotherapy. The invention further relates to a tumor-associated cytotoxic T cell (CTL) peptide epitope that serves as an active pharmaceutical ingredient of a vaccine combination that stimulates anti-tumor immune response singly or in combination with another tumor associated peptides. The invention relates to several peptide sequences derived from human tumor cell HLA class I and HLA class II molecules and variants thereof usable in a vaccine composition for eliciting anti-tumor immune response.SELECTED DRAWING: None
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Inventors:
JULIANE STICKEL
DANIEL KOWALEWSKI
HANS-GEORG RAMMENSEE
STEFAN STEVANOVIC
DANIEL KOWALEWSKI
HANS-GEORG RAMMENSEE
STEFAN STEVANOVIC
Application Number:
JP2019132609A
Publication Date:
January 30, 2020
Filing Date:
July 18, 2019
Export Citation:
Assignee:
IMMATICS BIOTECHNOLOGIES GMBH
International Classes:
C12N15/12; A61K35/12; A61K35/17; A61K35/76; A61K38/08; A61K38/10; A61K38/16; A61K38/17; A61K39/00; A61K48/00; A61P35/00; A61P35/02; C07K7/06; C07K7/08; C07K14/47; C07K14/725; C07K14/74; C07K19/00; C12N5/0783; C12N5/0784; C12N5/10; C12N15/62; C12N15/63; C12P21/02; C12Q1/02; C12Q1/6809; C12Q1/6869; G01N33/15; G01N33/50; G01N33/53; G01N37/00
Attorney, Agent or Firm:
Takashi Shoji