Title:
NOVEL INDOLE DERIVATIVE
Document Type and Number:
Japanese Patent JPS60132981
Kind Code:
A
Abstract:
This invention relates to novel indole derivatives of the formula (I) wherein A represents a -CH2-CH2-, -CH=CH-, group and B represents a methylene, carbonyl, or thiocarbonyl group or A represents a -CO-CO- or group and B represents a methylene group, E represents an alkylene group or a 2-hydroxy-n-propylene, 2-hydroxy-n-butylene, or 3-hydroxy-n-butylene group, G represents an alkylene group, R1 represents a hydrogen, chlorine, or bromine atom or a trifluoromethyl, nitro, amino, alkylamino, dialkylamino, alkyl, hydroxyl, alkoxy, or phenylalkoxy group, R2 represents a hydrogen, chlorine, or bromine atom or a hydroxyl, alkoxy, phenylalkoxy, or alkyl group or R1 and R2 together represent an alkylenedioxy group, R3 represents a hydrogen, chlorine, or bromine atom or an alkyl group, R4 represents a hydrogen atom or an alkyl or phenylalkyl group, R5 represents a hydrogen, fluorine, chlorine, or bromine atom or an alkyl, hydroxyl, alkoxy, or phenylalkoxy group, R6 represents a hydrogen atom or an alkoxy group, and R7 represents a hydrogen atom or an alkenyl, alkyl or phenylalkyl group, and the acid additional salts thereof. These compounds, which may be obtained by use of known methods, have valuable pharmacological properties, particularly a heart rate-lowering activity.
Inventors:
MANFURETSUDO RAIFUEN
YOHAHIMU HAIDAA
FUORUKUHARUTO AUSUTERU
NORUBERUTO HAUERU
BARUTAA KOBINGAA
KURISUCHIYAN RIRII
YOHAHIMU HAIDAA
FUORUKUHARUTO AUSUTERU
NORUBERUTO HAUERU
BARUTAA KOBINGAA
KURISUCHIYAN RIRII
Application Number:
JP25278684A
Publication Date:
July 16, 1985
Filing Date:
November 29, 1984
Export Citation:
Assignee:
THOMAE GMBH DR K
International Classes:
A61K31/55; A61P9/06; A61P9/08; A61P9/10; A61P25/02; C07C59/64; C07D209/14; C07D209/16; C07D209/18; C07D223/16; C07D403/12; C07D491/056; (IPC1-7): A61K31/55; C07D209/00; C07D209/14; C07D223/00; C07D223/16; C07D403/12
Attorney, Agent or Firm:
Asamura Akira