Title:
NOVEL ORGANIC COMPOUND*ITS MANUFACTURE AND COMPOSITION CONTAINING IT
Document Type and Number:
Japanese Patent JPS554385
Kind Code:
A
Abstract:
Coumpounds of the formula (I) wherein: n is 1 to 5 Y is -CH2-CH2, -CH=CH- or -C IDENTICAL C- R1 is hydrogen or CO2R1 represents an ester group in which the R1 moiety contains from 1-12 carbon atoms; R2 is hydrogen, C1-4 alkyl or phenyl; R3 is hydroxy or protected hydroxy; R4 is a group of the formula: L-Q-R10 in which Q is an oxygen atom, a -CH=CH- group or a -C IDENTICAL C- group, and L is a C1-9 alkylene group; and R10 is C1-4 alkyl, phenyl or naphthyl, any of which phenyl or naphthyl moieties may be substituted by one or more halogen, trifluoromethyl, C1-6 alkyl, hydroxy, C1-6 alkoxy, phenyl C1-6 alkoxy or nitro groups, or if Q is a -CH=CH- group, the R10 may be a hydrogen atom; and R5 is hydrogen or C1-6 alkyl; and salts thereof, having similar activity to natural prostaglandins, a process for their preparation, intermediates useful in that process and pharmaceutical compositions containing them.
Inventors:
DEIBITSUDO REJINARUDO ADAMUSU
ARAN FURANKU BAANESU
ARAN FURANKU BAANESU
Application Number:
JP7556379A
Publication Date:
January 12, 1980
Filing Date:
June 15, 1979
Export Citation:
Assignee:
BEECHAM GROUP LTD
International Classes:
A61K31/41; A61P1/04; A61P7/02; A61P9/06; A61P9/12; A61P43/00; C07C29/40; C07C41/26; C07C41/30; C07C43/12; C07C43/178; C07C43/23; C07C45/29; C07C45/30; C07C45/51; C07C47/198; C07C49/255; C07C309/73; C07D249/12; (IPC1-7): A61K31/41; C07D249/12
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