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Title:
NOVEL PHYSIOLOGICALLY ACTIVE SUBSTANCE SS33410 AND ITS PREPARATION
Document Type and Number:
Japanese Patent JPS6119494
Kind Code:
A
Abstract:

NEW MATERIAL:A physiologically active substance, SS33410 having following physicochemical properties: elementary analses in %, C 66.10, H 8.03; molecular weight: 790; molecular formula: C43H66O12; melting point: 131°C (decomposition); [α]D25=-21.0° [C=1% in chloroform/methanol (1:1)]; soluble in pyridine, dimethyl sulfoxide, chloroform, chloroform-methanol mixture, ethyl acetate, hard soluble in acetone, methanol, insoluble in n-hexane, ether and water; colorless column crystal which is acidic and hygroscopic; color reactions: red in vaniline- sulfuric acid, changing to dark brown by additional heating. Negative to Dragendroff's reaction.

USE: Anti-inflammatory.

PREPARATION: A strain of Streptomyces such as Streptomyces s.p-S33410 (FERM P-7679) is aerobically cultured, preferably through the submerged fermentation with agitation at 27°C for 3W7 days.


Inventors:
MOGI KINICHI
YANO KENICHI
ASAOKA TAKEMITSU
OONO JIYUNJI
OOKAWA JIYUNJI
YOKOI KOUICHI
NAKAJIMA TOSHIAKI
Application Number:
JP14032984A
Publication Date:
January 28, 1986
Filing Date:
July 06, 1984
Export Citation:
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Assignee:
SS PHARMACEUTICAL CO
International Classes:
C07G99/00; A61K35/74; A61P29/00; C12P1/06; C12R1/465; (IPC1-7): A61K35/74; C07G17/00; C12P1/06; C12R1/465
Attorney, Agent or Firm:
Ariga Miyuki