Title:
NOVEL POLYHALOGENOOSTEROID AND PREPARATION THEREOF
Document Type and Number:
Japanese Patent JPS5289662
Kind Code:
A
Abstract:
Novel 6 alpha ,9 alpha ,21-trihalogeno-11 beta -hydroxy-16 alpha or 16 beta -methyl-17 alpha -propionyloxy-pregn-4-ene-3,20-dione compounds of the formula (I) in which X represents chlorine or flourine, R represents the group -CH2CH-, -CH=CH- or -CH=CCl-, the chlorine atom being in the positon 2 of the steroid numbering, and in which the 16-methyl radical is alpha - or beta -oriented, are useful pharmaceuticals, especially anti-inflammatory agents for topical administration.
Inventors:
YAROSURAFU KARUFUODA
GEORUGU ANNERU
GEORUGU ANNERU
Application Number:
JP14932676A
Publication Date:
July 27, 1977
Filing Date:
December 11, 1976
Export Citation:
Assignee:
CIBA GEIGY AG
International Classes:
A61K31/57; A61P29/00; C07J5/00; C07J7/00; C07J21/00; C07J31/00; (IPC1-7): A61K31/57; C07J7/00