Title:
NOVEL POLYMORPH OF BRIMONIDINE TARTRATE AND PRODUCTION METHOD THEREOF
Document Type and Number:
Japanese Patent JP2015203011
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a novel polymorph of brimonidine tartrate and a production method thereof.SOLUTION: By suspending brimonidine tartrate technical product in acetone and purifying the suspension, a crystalline form brimonidine tartrate having a melting point of 199 to 205°C is obtained.
Inventors:
KANAZAWA HAJIME
Application Number:
JP2014082558A
Publication Date:
November 16, 2015
Filing Date:
April 14, 2014
Export Citation:
Assignee:
KAZUMA PARTNERS CO LTD
International Classes:
C07D403/12; A61K31/498; A61P27/02; A61P27/06
Domestic Patent References:
| JPS51149291A | 1976-12-22 |
Foreign References:
| RU2285003C1 | 2006-10-10 |
Other References:
有機化合物結晶作製ハンドブック−原理とノウハウ−, JPN6013036891, 25 July 2008 (2008-07-25), pages 57 - 79, ISSN: 0003648627
"第１部 剤形論（物理薬剤学）", 新・薬剤学総論（改訂第３版） INTRODUCTION TO MODERN PHARMACEUTICS, vol. 第1版, JPN6017036694, ISSN: 0003648628
"第１部 剤形論（物理薬剤学）", 新・薬剤学総論（改訂第３版） INTRODUCTION TO MODERN PHARMACEUTICS, vol. 第1版, JPN6017036694, ISSN: 0003648628
Attorney, Agent or Firm:
Mitsuo Kata
Hiroshi Sanaka
Hiroshi Sanaka