Title:
NOVEL PREPARATION OF ANTIBIOTIC NEOVIRIDOGRISEINS
Document Type and Number:
Japanese Patent JPS5959198
Kind Code:
A
Abstract:
PURPOSE: To prepare antibiotic neoviridogriseins, especially neoviridogrisein IIselectively, by cultivating a bacterium belonging to the genus Streptomyces.
CONSTITUTION: A variant such as Streptomyces sp.G-89 (FERM-P 184) belonging to the genus Streptomyces, capable of producing antibiotic neoviridogriseins shown by the formula (R is hydrogen, or hydroxyl group), deficient in prolylhydroxylase activity, is inoculated into a nutrient medium, cultivated at 24W 33°C at 6W9pH under aerobic conditions, and antibiotic neoviridog riseins consisting essentially of antibiotic neoviridogrisein II wherein R is hydrogen atom in the formula is collected from the culture solution.
Inventors:
OKUMURA YASUSHI
NAGATO NOBUO
OONISHI MASAHIRO
OKAMOTO ROKUROU
ISHIKURA TOMOYUKI
NAGATO NOBUO
OONISHI MASAHIRO
OKAMOTO ROKUROU
ISHIKURA TOMOYUKI
Application Number:
JP17244282A
Publication Date:
April 04, 1984
Filing Date:
September 29, 1982
Export Citation:
Assignee:
SANRAKU OCEAN CO
International Classes:
C12N1/20; C12P21/02; C12P21/04; C12R1/465; (IPC1-7): C12N1/20; C12P21/04
Attorney, Agent or Firm:
Arai