NOVEL SELECTIVE INHIBITOR TO VIRUS OR BACTERIAL NEURAMINIDASE

Japanese Patent JP2006036770

A

To selectively inhibit virus (particularly influenza virus), especially glycolytic enzymes like neuraminidase, above all, viral or bacterial neuraminidase.

Novel compounds of Formula (III) or Formula (IV) are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or an N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of this invention are also described.

JP3417969	FLUOROINDENE RING DERIVATIVE COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME
WO/2020/262648	ACRYLIC ESTER DERIVATIVE, AND APPLICATION AND PRODUCTION INTERMEDIATE THEREOF

BISCHOFBERGER NORBERT W
KIM CHOUNG U
LEW WILLARD
LIU HONGTAO
WILLIAMS MATTHEW A

JP2005207906A

February 09, 2006

July 15, 2005

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GILEAD SCIENCES INC (US)

C07C69/75; A61K31/13; C07D277/20; A61K31/185; A61K31/19; A61K31/195; A61K31/196; A61K31/215; A61K31/221; A61K31/33; A61K31/336; A61K31/35; A61K31/351; A61K31/357; A61K31/395; A61K31/396; A61K31/40; A61K31/4015; A61K31/425; A61K31/426; A61K31/44; A61K31/443; A61K31/4433; A61K31/445; A61K31/66; A61K31/675; A61P31/04; A61P31/12; A61P31/16; A61P43/00; C07B53/00; C07C69/757; C07C233/52; C07C233/63; C07C247/14; C07C257/16; C07C279/16; C07C311/07; C07C311/14; C07C317/46; C07C321/22; C07C323/61; C07C323/63; C07D203/08; C07D203/26; C07D207/27; C07D207/40; C07D211/68; C07D213/74; C07D257/04; C07D277/40; C07D303/40; C07D309/28; C07D311/14; C07D317/72; C07D327/10; C07D405/04; C07D409/04; C12N9/99; C12Q1/34; C07D335/00

JPH05507068A	1993-10-14
JP3300365B2	2002-07-08
JP4234917B2	2009-03-04

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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