Title:
NOVEL SMALL-MOLECULE INHIBITOR FOR TEAD TRANSCRIPTION FACTOR
Document Type and Number:
Japanese Patent JP2023113615
Kind Code:
A
Abstract:
To provide a novel compound that is useful in the treatment of diseases associated with TEAD transcription factor activity.SOLUTION: The problem is solved by a compound of formula (I), or a pharmaceutically acceptable salt thereof. [L1 is absent or substituted/unsubstituted amino group; D is a substituted aryl group, etc.; A6 to A10 are substituted/unsubstituted C or N].SELECTED DRAWING: Figure 1-1
Inventors:
PRANAB MAITI
CHANDRASEKHAR ABBINENI
KRISHNA CHAITANYA TALLURI
SUNIL KUMAR PANIGRAHI
WU XU
GOPALA KRISHNA JARUGUMILLI
SUN YANG
CHANDRASEKHAR ABBINENI
KRISHNA CHAITANYA TALLURI
SUNIL KUMAR PANIGRAHI
WU XU
GOPALA KRISHNA JARUGUMILLI
SUN YANG
Application Number:
JP2023076091A
Publication Date:
August 16, 2023
Filing Date:
May 02, 2023
Export Citation:
Assignee:
MASSACHUSETTS GEN HOSPITAL
International Classes:
C07C211/50; A61K31/136; A61K31/166; A61K31/196; A61K31/245; A61K31/277; A61K31/351; A61K31/397; A61K31/41; A61K31/415; A61K31/4164; A61K31/426; A61K31/44; A61K31/4402; A61K31/4439; A61K31/444; A61K31/445; A61K31/4965; A61K31/505; A61K31/5375; A61P35/00; A61P35/02; C07C229/40; C07C229/46; C07C229/56; C07C233/57; C07C235/16; C07C237/20; C07C237/40; C07C255/58; C07C271/22; C07C275/40; C07C311/18; C07C317/36; C07D205/04; C07D211/26; C07D211/60; C07D213/71; C07D213/74; C07D213/79; C07D213/80; C07D213/82; C07D213/84; C07D231/38; C07D239/28; C07D239/47; C07D239/48; C07D241/20; C07D241/28; C07D257/04; C07D277/28; C07D277/42; C07D295/135; C07D295/155; C07D309/14; C07D401/12; C07D491/107
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Yukiko Uetake
Norio Omori
Yukiko Uetake