NOVEL TREATMENT DRUG COMPOSITION - BEECHAM WUELFING GMBH & CO KG

Title:

NOVEL TREATMENT DRUG COMPOSITION

Document Type and Number:

Japanese Patent JPH01319429

Kind Code:

A

Abstract:

PURPOSE: To obtain a pharmaceutical composition containing 5-HT1A agonist as an active ingredient and used for treatment and prophylaxis of disorders associated with neuronal degeneration resulting from ischemic events in mammals. CONSTITUTION: This composition contains 8-hydroxy-2-(di-n-propylamino) tetralin and a pharmaceutically permissible carrier. The composition is used as a unit dose composition containing 1-500mg, preferably 2-50mg agonist and the daily dose is 0.01-15mg/kg, preferably 1-4mg/kg and is effective to the treatment or prophylaxis of disorders associated with neuronal degeneration resulting from ischemic events, including cerebral ischemia after cardiac arrest, stroke and multi-infarct dementia and also ischemic events such as those resulting from surgery and newborns during birth.

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Inventors:

CHIYAARUZU DEBITSUDO NIKORUSON
YOHANESU YUUKUNA

Application Number:

JP11401389A

Publication Date:

December 25, 1989

Filing Date:

May 06, 1989

Export Citation:

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Assignee:

BEECHAM WUELFING GMBH & CO KG

International Classes:

A61K45/06; A61K31/00; A61K31/13; A61K31/135; A61K45/00; A61P9/00; A61P9/10; A61P25/28; A61P43/00; (IPC1-7): A61K31/135; A61K45/06

Attorney, Agent or Firm:

Masamitsu Akizawa (1 person outside)

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