Title:
NUCLEAR TRANSFER WITH DIFFERENTIATED FETAL AND ADULT DONOR CELLS
Document Type and Number:
Japanese Patent JP2007167078
Kind Code:
A
Abstract:
To provide an improved method of nuclear transfer, wherein the resultant nuclear transfer units are useful for multiplication of genotypes and transgenic genotypes by the production of fetuses and offspring, and for production of isogenic CICM cells, including human isogenic embryonic or stem cells, and production of genetically engineered or transgenic mammalian embryos, fetuses and offspring is also facilitated by the present method since the differentiated cell source of the donor nuclei can be genetically modified and clonally propagated.
Disclosed is a method of nuclear transfer involving the transplantation of donor differentiated cell nuclei into enucleated oocytes of the same species as the donor cell.
Inventors:
STEVEN L STICE
CIBELLI JOSE
ROBL JAMES
PAUL GOLUEKE
PONCE DE LEON F ABEL
D JOSEPH JERRY
CIBELLI JOSE
ROBL JAMES
PAUL GOLUEKE
PONCE DE LEON F ABEL
D JOSEPH JERRY
Application Number:
JP2007084406A
Publication Date:
July 05, 2007
Filing Date:
March 28, 2007
Export Citation:
Assignee:
UNIV OF MASSACHUSETTS A PUBLIC
International Classes:
A01K67/02; A01K67/027; C12N5/10; A61P1/18; A61P3/10; A61P9/00; A61P9/04; A61P13/02; A61P17/02; A61P21/00; A61P25/16; A61P25/28; A61P31/18; A61P35/00; C12N5/073; C12N15/09; C12N15/877; A61K35/12
Attorney, Agent or Firm:
Minoru Nakamura
Fumiaki Otsuka
Sadao Kumakura
Shishido Kaichi
Nobuo Ogawa
Takaki Nishijima
Atsushi Hakoda
Fumiaki Otsuka
Sadao Kumakura
Shishido Kaichi
Nobuo Ogawa
Takaki Nishijima
Atsushi Hakoda
Previous Patent: SEEDLING CULTIVATION SYSTEM FOR REED GRASS
Next Patent: COLLAGEN-INCLUDING ACIDIC FOOD AND DRINK
Next Patent: COLLAGEN-INCLUDING ACIDIC FOOD AND DRINK