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Title:
ヌクレオチドおよびヌクレオシド組成物ならびにこれらに関連する使用
Document Type and Number:
Japanese Patent JP7045411
Kind Code:
B2
Abstract:
This disclosure relates to nucleotide and nucleoside therapeutic compositions and uses in treating infectious diseases, viral infections, and cancer, where the base of the nucleotide or nucleoside contains at least one thiol, thione or thioether.

Inventors:
Dennis Sea Liotta
George Earl Painter
Gregory Earl Blooming
Abel de la Rosa
Application Number:
JP2020077187A
Publication Date:
March 31, 2022
Filing Date:
April 24, 2020
Export Citation:
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Assignee:
Emory University
International Classes:
C07H19/10; A61K9/127; A61K31/7068; A61P31/12; A61P31/14; A61P31/16; A61P31/18; A61P31/20; A61P31/22; A61P43/00; C07H19/11
Domestic Patent References:
JP2005504087A
JP2005536640A
JP2004510698A
JP2004533401A
JP2004513083A
JP2010532747A
JP2010280660A
JP2007204485A
JP10007694A
Foreign References:
US3804826
Other References:
BRACHWITZ,H. et al,1-β-D-Arabinofuranosylcytosine-5'-alkylphosphonophosphates and diphosphates: new orally active derivatives of ara-C,Journal of Lipid Research,1998年,Vol.39, No.1,pp.162-172
Antiviral Chemistry & Chemotherapy,1999年,Vol.10, No.4,pp.195-209
Nucleosides, Nucleotides and Nucleic Acids,2003年,Vol.22, No.10,pp.1867-1897
Bioorganic & Medicinal Chemistry,2008年,Vol.16, No.12,pp.6319-6332
Nucleosides & Nucleotides,1997年,Vol.16, No.7-9,pp.1099-1102
Attorney, Agent or Firm:
Kawaguchi International Patent Office