To obtain a nutrient supplimentary composition for increasing the arthrodial cartilage regeneration facilitative effect of glucosamine.

This nutrient supplimentary composition is obtained by using glucosamine sulfate or glucosamine hydrochloride in combination with a bone marrow extract as active ingredients and administrated to patients in order to prevent and treat diseases relevant to the degeneration or deformation of arthrodial cartilage represented by osteoarthritis. In comparison with the single dose of glucosamine, the improvement ratio particularly on female patients is drastically increased.