Title:
Ｏ－置換ヒドロキサム酸
Document Type and Number:
Japanese Patent JP7194436
Kind Code:
B2
Abstract:
O-substituted hydroxamic acids with carbon-based leaving groups as HNO donors are disclosed. Pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions also are disclosed.
Inventors:
John Pea Tuscano
Sagar Norian
Darryl A. Guthrie
Sagar Norian
Darryl A. Guthrie
Application Number:
JP2019503988A
Publication Date:
December 22, 2022
Filing Date:
July 27, 2017
Export Citation:
Assignee:
THE JOHNS HOPKINS UNIVERSITY
International Classes:
C07D231/28; A61K31/37; A61K31/4152; A61K31/515; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P35/00; C07D239/62; C07D311/56
Domestic Patent References:
| JP2015501308A | ||||
| JP2002511092A |
Foreign References:
| US20150344437 |
Other References:
Frazier, Charles P. et.al.,Electrophilic α-oxygenation reaction of β-ketoesters using N-hydroxycarbamates: control of the ambident reactivity of nitrosoformate intermediates,Chemical Science,2013年,Vol.4(10),p.3857-3862
Attorney, Agent or Firm:
Yamato Kento
Shinagawa
Wu Yingyan
Futami Kamahira
Masahiro Suwon
Shinagawa
Wu Yingyan
Futami Kamahira
Masahiro Suwon