Title:
オリゴマー−抗コリン剤複合体
Document Type and Number:
Japanese Patent JP5877553
Kind Code:
B2
Abstract:
The invention provides small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different as compared to the characteristics of the small molecule drug not attached to the water-soluble oligomer.
Inventors:
Riggs-Saucer, Jennifer
Den, Bo-Liang
Den, Bo-Liang
Application Number:
JP2009553621A
Publication Date:
March 08, 2016
Filing Date:
March 13, 2008
Export Citation:
Assignee:
Nectar Therapeutics
International Classes:
C07C219/20; A61K31/221; A61K45/00; A61K47/34; A61K47/48; A61P13/00
Domestic Patent References:
| JP2002517464A | ||||
| JP2007514761A | ||||
| JP2010521465A | ||||
| JP2010522142A | ||||
| JP2013253104A |
Other References:
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,1976年,Vol.11,No.6,p.525-526
CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS,2000年1月1日,Vol.17,No.2,p.101,114
Eur.Polym.J.,1983年,Vol.19,No.12,p.1177-1183
J.Clin.Pharmacol.,2001年,Vol.41,p.636-644
Clinical Therapeutics,2005年,Vol.27,No.2,p.144-153
CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS,2000年1月1日,Vol.17,No.2,p.101,114
Eur.Polym.J.,1983年,Vol.19,No.12,p.1177-1183
J.Clin.Pharmacol.,2001年,Vol.41,p.636-644
Clinical Therapeutics,2005年,Vol.27,No.2,p.144-153
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto