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Title:
OLOPATADINE FORMULATION FOR TOPICAL ADMINISTRATION
Document Type and Number:
Japanese Patent JP2012107046
Kind Code:
A
Abstract:

To provide topical formulations of olopatadine used for treating allergic or inflammatory disorders of an eye and a nose.

The aqueous formulations contain approximately 0.17-0.62% (w/v) of olopatadine and an amount of polyvinylpyrrolidone or polystyrene sulfonic acid sufficient to enhance the physical stability of the formulations. The solution formulations topically administrable for treating the allergic or inflammatory disorders of the eye and the nose contain 0.17-0. 62% (w/v) olopatadine and a polymeric physical stability-enhancing ingredient consisting essentially of polyvinylpyrrolidone or polystyrene sulfonic acid in an amount sufficient to enhance the physical stability of the solution.


Inventors:
CASTILLO ERNESTO J
HAN WESLEY WEHSIN
ZHANG HUIXIANG
BHAGAT HARESH G
SINGH ONKAR N
BULLOCK JOSEPH PAUL
DIXIT SURESH C
Application Number:
JP2012035170A
Publication Date:
June 07, 2012
Filing Date:
February 21, 2012
Export Citation:
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Assignee:
ALCON INC
International Classes:
A61K9/08; A61K9/00; A61K31/335; A61K47/32; A61K47/34; A61K47/38; A61K47/46; A61P11/02; A61P27/14; A61P29/00; A61P37/08
Domestic Patent References:
JP2010150292A2010-07-08
Foreign References:
WO2000024375A12000-05-04
WO2001054687A12001-08-02
US5641805A1997-06-24
WO2000024375A12000-05-04
WO2001054687A12001-08-02
US5641805A1997-06-24
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita