Title:
眼科用組成物及びその製造方法
Document Type and Number:
Japanese Patent JP7192766
Kind Code:
B2
Abstract:
Provided is an ophthalmic composition from which sesame oil or castor oil can be released easily by the dilution with a tear fluid and therefore the sesame oil or castor oil can be supplied to a tear oil layer. An ophthalmic composition containing (A) at least one oil selected from (A-1) sesame oil and (A-2) castor oil and (B) a nonionic surfactant selected from (B-1) polyoxyethylene castor oil, (B-2) polyoxyethylene hydrogenated castor oil and (B-3) another nonionic surfactant, wherein the blend ratios of these components by mass meet the following requirement: 0.05 ≤ [(B-1)+(B-2)+(B-3)]/(A)[(B-1)/0.5+(B-2)/0.5+(B-3)/0.05]/[(A-1)+(A-2)]×(A-1)/[(A-1)+(A-2)]+[(B-1)/0.2+(B-2)/0.25+(B-3)/0.05]/[(A-1)+(A-2)]×(A-2)/[(A-1)+(A-2)] ≤ 10.0, and the permeability of the composition is 70% or more.
Inventors:
Aimi Tanaka
Masataka Yoshida
Hiromi Takamura
Masataka Yoshida
Hiromi Takamura
Application Number:
JP2019513679A
Publication Date:
December 20, 2022
Filing Date:
April 19, 2018
Export Citation:
Assignee:
LION Corporation
International Classes:
A61K36/185; A61K9/107; A61K31/23; A61K36/47; A61K47/10; A61K47/14; A61K47/26; A61K47/44; A61P27/04
Domestic Patent References:
| JP2012144527A | ||||
| JP2008273959A | ||||
| JP2012528876A |
Foreign References:
| WO2013008714A1 |
Attorney, Agent or Firm:
Patent Attorney Corporation Eimei International Patent Office