Title:
OPHTHALMIC OIL-IN-WATER TYPE EMULSION WITH STABLE POSITIVE ZETA POTENTIAL
Document Type and Number:
Japanese Patent JP2012149102
Kind Code:
A
Abstract:
To provide a stable ophthalmic oil-in-water type emulsion for a long period of time.
The ophthalmic oil-in-water type emulsion comprises colloid particles having an oily core surrounded by an interfacial film, at least one cationic agent, and at least one non ionic surfactant, has a positive zeta potential, and meets zeta potential stability Test A requirements. A method for making the emulsions is provided. A delivery device for the ophthalmic oil-in-water type emulsion selected from the group comprising lenses, an ocular patch, an implant, and an insert is provided.
Inventors:
BAGUE SEVERINE
PHILIPS BETTY
RABINOVICH-GUILATT LAURA
LAMBERT GREGORY
GARRIGUE JEAN-SEBASTIEN
PHILIPS BETTY
RABINOVICH-GUILATT LAURA
LAMBERT GREGORY
GARRIGUE JEAN-SEBASTIEN
Application Number:
JP2012111941A
Publication Date:
August 09, 2012
Filing Date:
May 15, 2012
Export Citation:
Assignee:
NOVAGALI PHARMA SA
International Classes:
A61K47/18; A61K9/107; A61K31/436; A61K31/706; A61K38/00; A61K47/16; A61K47/24; A61K47/34; A61K47/36; A61P27/02; A61P27/04; A61P27/06; A61P27/14; A61P31/00; A61P35/00
Domestic Patent References:
| JPH1129483A | 1999-02-02 | |||
| JPH0899867A | 1996-04-16 | |||
| JP2005206598A | 2005-08-04 | |||
| JP2006117656A | 2006-05-11 | |||
| JP2004359629A | 2004-12-24 | |||
| JP2004315365A | 2004-11-11 | |||
| JP5122969B2 | 2013-01-16 |
Attorney, Agent or Firm:
Masayuki Masabayashi
Hayashi Ichiyoshi
Hayashi Ichiyoshi