Title:
ジヒドロ-2,3-ベンゾジアゼピンの光学異性体及びその立体選択的合成
Document Type and Number:
Japanese Patent JP2009522245
Kind Code:
A
Abstract:
The present invention relates to dihydro-2,3-benzodiazepine compounds of high enantiomeric purity according to the general formula (I), which contain an asymmetric centre at the position 4 of the dihydro-2,3-benzodiazepine compound, and the preparation thereof and the used intermediates as well. These compounds have anti-convulsiveA muscle relaxant and neuroprotective effect due their non-competitive AMPA antagonistic properties.
Inventors:
Istvan Ring
Youzhev Balcozi
Zoltan Greff
Garbol Senasi
Garbol Guigrel
Savorchu Kerutesu
Dura Schu
Mihai Albert
Garbol capsh
Geeza Sabo
Michloche Vague
Marta Argoston
Jersey levi
Christina Mauritz
Larslaw Garbour Haarsing
Youzhev Balcozi
Zoltan Greff
Garbol Senasi
Garbol Guigrel
Savorchu Kerutesu
Dura Schu
Mihai Albert
Garbol capsh
Geeza Sabo
Michloche Vague
Marta Argoston
Jersey levi
Christina Mauritz
Larslaw Garbour Haarsing
Application Number:
JP2008548033A
Publication Date:
June 11, 2009
Filing Date:
December 29, 2006
Export Citation:
Assignee:
Aegis Gyoji Seldjar Nirvano San Michelede Race Venital Sasague
International Classes:
C07D243/10; A61K31/551; A61P1/08; A61P13/02; A61P21/02; A61P25/00; A61P25/04; A61P25/06; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/28; A61P35/00; C07D243/28; C07D403/06; C07B53/00
Attorney, Agent or Firm:
Soichi Takezawa
Noritsugu Nakama
Hiroyuki Mori
Noritsugu Nakama
Hiroyuki Mori