Title:
複製欠損性組換えウイルスワクチン中の抗原に対する細胞傷害性T細胞応答に有利である反復ワクチン接種と組み合わされた最適化初期-後期プロモーター
Document Type and Number:
Japanese Patent JP2012520061
Kind Code:
A
Abstract:
The present invention relates to a replication deficient recombinant virus encoding at least one antigen and/or antigenic epitope, wherein expression of said antigen and/or antigenic epitope is regulated by a transcriptional control element comprising at least two elements driving early expression of said antigen and/or antigenic epitope and the use of said replication deficient recombinant virus as medicament or vaccine.
Inventors:
Brinkman Kai
Baul Karen
Hausmann Jürgen
Baul Karen
Hausmann Jürgen
Application Number:
JP2011553357A
Publication Date:
September 06, 2012
Filing Date:
March 11, 2010
Export Citation:
Assignee:
Bavarian Nordic Actiselskab
International Classes:
C12N15/09; A61K39/12; A61K39/235; A61K39/245; A61K39/275; A61P43/00; C12N7/04
Other References:
JPN6014017302; Ｊｏｕｒｎａｌ ｏｆ Ｖｉｒｏｌｏｇｙ ｖｏｌ．６５， ｎｏ．１０, 1991, ｐ．５５８４-５５８８
Attorney, Agent or Firm:
Mitsufumi Esaki
Blacksmith
Katsunori Uenishi
Ichiro Torayama
Blacksmith
Katsunori Uenishi
Ichiro Torayama