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Title:
経口用医薬組成物及びその製造方法
Document Type and Number:
Japanese Patent JP7149449
Kind Code:
B2
Abstract:
Provided is a pharmaceutical composition for orally administering a pharmaceutical active ingredient which has a pH-dependent solubility profile, said pharmaceutical composition making it possible to achieve excellent scrubbing efficiency regardless of the pH inside the alimentary canal. Said oral pharmaceutical composition contains a pharmaceutical active ingredient which has a pH-dependent solubility profile, an inorganic or organic acid, and a hydrophilic polymer.

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Inventors:
Akira Tanaka
Chiaki Funatani
Kenichi Kura
Kimura Tadashi
Application Number:
JP2022529745A
Publication Date:
October 06, 2022
Filing Date:
July 01, 2021
Export Citation:
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Assignee:
ARTham Therapeutics Inc.
International Classes:
A61K31/5377; A61K9/10; A61K9/16; A61K47/02; A61K47/04; A61K47/12; A61K47/18; A61K47/22; A61K47/32; A61K47/34; A61K47/38; A61P9/00; A61P35/00
Domestic Patent References:
JP2009504796A
JP2004518676A
JP2009504795A
JP2019510059A
JP2017002034A
Foreign References:
WO2016175230A1
Other References:
PATEL, Chirag G. et al.,Characterizing the Sources of Pharmacokinetic Variability for TAK-117 (Serabelisib), an Investigatio,Clinical Pharmacology in Drug Development,2019年,Vol.8, No.5,pp.637-646,ISSN: 2160-7648
PATEL, C. et al.,Clinical biopharmaceutic assessments of the sources of absorption variability for the anticancer age,Clinical Pharmacology and Therapeutics,2017年,Vol.101, Supplement 1,p.S82, Abstract Number PII-110,ISSN: 1532-6535
Attorney, Agent or Firm:
Aoki Atsushi
Shinji Mihashi
Youichi Watanabe
Nakajima Masaru
Tatsunori Ikeda