Title:
優れた硬度と崩壊性を有する経口医薬組成物
Document Type and Number:
Japanese Patent JP7112184
Kind Code:
B2
Abstract:
To provide an oral pharmaceutical composition, particularly a tablet quickly disintegrating in the oral cavity having a less decrease in hardness even after stored under high humidity conditions and excellent hardness and disintegration properties.SOLUTION: There is provided an oral pharmaceutical composition which comprises a pharmaceutically active ingredient or a pharmaceutically acceptable salt thereof, one or more additives selected from a sugar or a sugar alcohol and a disintegrator, wherein the pharmaceutically active ingredient or a pharmaceutically acceptable salt thereof preferably is galantamine or a salt thereof, more preferably galantamine hydrobromide, the sugar or the sugar alcohol preferably is one or more selected from mannitol, trehalose, xylitol, erythritol, lactose, glucose and sucrose, preferably mannitol and the disintegrator is carmellose.SELECTED DRAWING: None
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Inventors:
Keisuke Kido
Ayaka Koga
Yasunori Adachi
Ayaka Koga
Yasunori Adachi
Application Number:
JP2017116272A
Publication Date:
August 03, 2022
Filing Date:
June 13, 2017
Export Citation:
Assignee:
Nichi-Iko Gifu Factory Co., Ltd.
International Classes:
A61K31/55; A61K9/20; A61K47/26; A61K47/38; A61P25/28
Domestic Patent References:
| JP2018177706A | ||||
| JP2017052754A | ||||
| JP2002255796A |
Foreign References:
| WO2009102038A1 | ||||
| WO2011019045A1 | ||||
| CN104177368A |
Attorney, Agent or Firm:
Kaichi Otani