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Title:
低用量のエストラジオールを含む経口固形製剤
Document Type and Number:
Japanese Patent JP2008518895
Kind Code:
A
Abstract:
The present invention relates to oral solid dosage forms containing a very low dose of estradiol. The dosage forms are formulated in a manner so as to avoid degradation of the estradiol and to minimise the content of polyvinylpyrrolidone, while still achieving similar fast dissolution of the estradiol. The dosage forms are useful in preventing or treating a physical condition in a woman caused by insufficient endogenous levels of estradiol.

Inventors:
Funke, Adrian
Muller, Christina
Wagner, Torsten
Turt, Christian
Application Number:
JP2007538360A
Publication Date:
June 05, 2008
Filing Date:
November 01, 2005
Export Citation:
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Assignee:
Bayer Schering Pharma Aktiengesellschaft
International Classes:
A61K31/565; A61K9/26; A61K47/32; A61K47/36; A61K47/38; A61P1/08; A61P5/30; A61P15/12; A61P19/08; A61P19/10; A61P25/02; A61P25/04; A61P25/06; A61P25/24; A61P43/00; C07J1/00
Domestic Patent References:
JP2003048836A2003-02-21
JP2004512369A2004-04-22
JP2004155779A2004-06-03
JP2002509524A2002-03-26
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Shintaro Koike