To provide an organ regeneration device capable of regenerating a partially defective organ into a normal state.

This organ regeneration device 1 adapted to be used by placing it into a defective portion of an organ to regenerate the organ includes: a base body 2 having a shape corresponding to a shape of the defective portion of the organ; particles 3 carried on the base body 2, wherein the particles are composed of a different material from that of the base body 2; and a growth-related substance carried on at least one of the base body 2 and the particles 3. Preferably, for example, the growth-related substance contains an angiogenesis factor. Aside from this, the growth-related substance preferably contains nucleic acid containing a base sequence coding for amino-acid sequence of a growth factor different from the angiogenesis factor. Furthermore, the nucleic acid is preferably introduced into a host cell.