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Patent Searching and Data


Title:
ORGANIC COMPOUND AND ANTIDEPRESSIVE MEDICINE CONTAINING IT AS ACTIVE COMPONENT
Document Type and Number:
Japanese Patent JPS54151949
Kind Code:
A
Abstract:
The pharmaceutical compositions contain cis- and trans-N-(2-aminocyclopentyl)-N-acylanilides of the general formula and their pharmacologically acceptable acid addition salts. The substituents are defined in Claim 1. These pharmaceutical agents are preferably prepared by reacting a cyclopentene oxide with an aniline in the presence of a strong acid. This intermediate can be reacted first with a carboxylic anhydride and then with a base. The resulting alcohol is oxidised to the ketone, and the latter is finally converted using a primary or secondary amine and a reducing agent into the required final product. The acid addition salts are then obtained in known ways. The pharmaceutical compositions are antidepressants.

Inventors:
JIEIKOBU SUZUMUSUZUKOBITSUTSU
Application Number:
JP4340379A
Publication Date:
November 29, 1979
Filing Date:
April 10, 1979
Export Citation:
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Assignee:
UPJOHN CO
International Classes:
A61K31/16; A61K31/165; A61P25/24; A61P25/26; C07C67/00; C07C231/00; C07C233/00; C07C233/02; C07C233/41; C07C233/62; C07C235/14; C07C235/16; C07C239/00; C07C271/28; C07C291/04; C07C325/00; C07C327/40; C07C327/46; C07C333/24; (IPC1-7): A61K31/16; C07C103/44; C07C103/64; C07C103/737; C07C135/02; C07C153/05