Title:
有機化合物
Document Type and Number:
Japanese Patent JP6542236
Kind Code:
B2
Abstract:
The invention provides novel compounds, composition comprising said compounds and methods for inhibiting CK1 as well as methods of treating CK1 related disorders such as Alzheimer's disease comprising administering a therapeutically effective amount of a CK1 inhibitor to a patient in need thereof.
Inventors:
Jean chiang
Youi Pong
Pong Li
David Jay Beard
Lawrence Pee Wenogle
John Tomesh
Youi Pong
Pong Li
David Jay Beard
Lawrence Pee Wenogle
John Tomesh
Application Number:
JP2016545898A
Publication Date:
July 10, 2019
Filing Date:
January 09, 2015
Export Citation:
Assignee:
INTRA-CELLULAR THERAPIES, INC.
International Classes:
C07D487/04; A61K31/519; A61K51/00; A61P3/04; A61P9/10; A61P13/10; A61P21/02; A61P25/00; A61P25/04; A61P25/06; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P25/32; A61P25/34; A61P25/36; A61P27/02
Domestic Patent References:
| JP4503205A | ||||
| JP2010533686A | ||||
| JP2010531342A |
Foreign References:
| WO2013147711A1 | ||||
| WO2013104575A1 | ||||
| WO2012156756A1 |
Other References:
Masharipov, S. M. et al.,Acylation of 2-guanidinedinebenzimidazole and 2-cyanoamidobenzimidazoles by acid chlorides of unsaturated acids,O'zbekiston Kimyo Jurnali ,2001年,(4),39-41
REGISTRY(STN)[online],2013年12月 5日,[検索日 2018.09.11]CAS登録番号 1488130-69-3, 1480367-63-2, 1464177-09-0, 1371193-87-1, 1347086-77-4, 1306165-12-7, 1303672-10-7, 1292030-08-0, 1181955-69-0, 1180428-95-8, 1180151-24-9, 1179430-59-1, 1173045-98-1, 1172963-03-9, 1170380-95-6, 1170246-41-9, 1158418-74-6, 1147357-94-5, 1104077-34-0, 1103955-95-8, 1095881-07-4, 1083186-82-6, 1018285-50-1, 1016777-46-0, 1016760-54-5, 1016683-91-2, 1016518-08-3, 1014583-47-1, 1013244-91-1, 1010210-32-8, 1002853-32-8, 1002852-57-4
REGISTRY(STN)[online],2008年 2月11日,[検索日 2018.09.11]CAS登録番号 1002686-85-2, 1002686-48-7, 1001839-85-5, 955738-44-0, 954094-21-4, 954018-17-8, 954018-05-4, 953961-30-3, 925401-73-6, 924426-49-3, 924243-51-6, 923000-30-0, 923000-28-6, 922701-00-6, 922700-76-3, 885902-72-7, 880282-18-8, 847841-19-4, 802964-36-9, 764701-54-4, 762250-52-2, 728941-65-9, 723251-36-3, 638148-03-5, 561294-63-1,, 404586-30-7, 349415-75-4, 333433-38-8, 333413-24-4
REGISTRY(STN)[online],2013年12月 5日,[検索日 2018.09.11]CAS登録番号 1488130-69-3, 1480367-63-2, 1464177-09-0, 1371193-87-1, 1347086-77-4, 1306165-12-7, 1303672-10-7, 1292030-08-0, 1181955-69-0, 1180428-95-8, 1180151-24-9, 1179430-59-1, 1173045-98-1, 1172963-03-9, 1170380-95-6, 1170246-41-9, 1158418-74-6, 1147357-94-5, 1104077-34-0, 1103955-95-8, 1095881-07-4, 1083186-82-6, 1018285-50-1, 1016777-46-0, 1016760-54-5, 1016683-91-2, 1016518-08-3, 1014583-47-1, 1013244-91-1, 1010210-32-8, 1002853-32-8, 1002852-57-4
REGISTRY(STN)[online],2008年 2月11日,[検索日 2018.09.11]CAS登録番号 1002686-85-2, 1002686-48-7, 1001839-85-5, 955738-44-0, 954094-21-4, 954018-17-8, 954018-05-4, 953961-30-3, 925401-73-6, 924426-49-3, 924243-51-6, 923000-30-0, 923000-28-6, 922701-00-6, 922700-76-3, 885902-72-7, 880282-18-8, 847841-19-4, 802964-36-9, 764701-54-4, 762250-52-2, 728941-65-9, 723251-36-3, 638148-03-5, 561294-63-1,, 404586-30-7, 349415-75-4, 333433-38-8, 333413-24-4
Attorney, Agent or Firm:
Takuji Yamada
Aoyama Aoi
Michiko Matsutani
Yasushi Ochiai
Aoyama Aoi
Michiko Matsutani
Yasushi Ochiai